Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11217225 | 0.92 | CYP1A2 (0.58) | CYP1A2CYP2C9LMNATDP1TSHR | |
| SCHEMBL5484470 | 0.89 | CYP1A2 (0.63) | CYP1A2CYP2C9TSHRTP53CNR1 | |
| SCHEMBL335422 | 0.89 | CYP1A2 (0.59) | CYP1A2CYP2C9LMNATSHRALDH1A1 | |
| SCHEMBL9436866 | 0.89 | CYP1A2 (0.59) | CYP1A2CYP2C9TDP1CNR1CNR2 | |
| SCHEMBL6277409 | 0.89 | CYP1A2 (0.59) | CYP1A2CYP2C9LMNATDP1PIK3CA | |
| SCHEMBL31278334 | 0.89 | CYP1A2 (0.59) | CYP1A2CYP2C9LMNATSHRALDH1A1 | |
| SCHEMBL10752281 | 0.88 | CYP1A2 (0.58) | CYP1A2CYP2C9CNR1CNR2NPC1 | |
| SCHEMBL19433083 | 0.87 | CYP1A2 (0.59) | CYP1A2CYP2C9TSHRTP53MEN1 | |
| P-Xylene SCHEMBL3752326 | 0.86 | CYP1A2 (0.70) | CYP1A2CYP2C9TSHRTP53ALDH1A1 | |
| SCHEMBL9875276 | 0.86 | CYP1A2 (0.55) | CYP1A2CYP2C9LMNACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990002-B1 | DEXTRAN DERIVATIVES, PREPARATION METHOD AND APPLICATIONS AS MEDICINE WITH SPECIFIC BIOLOGICAL ACTION | BIODEX (FR) | 2005-10-05 | — | — | EP | claimed |
| US-6646120-B1 | Polysaccharides with side chains of methylcarboxylate, carboxymethylbenzylamide, sulfate and sulfonate groups; use as anti-thrombotic, substitute for plasma and modulator of cell proliferation | BIODEX (FR) | 2003-11-11 | — | — | US | claimed |
| US-4275159-A | IMMOBILIZATION | PROJEKTIERUNG CHEMISCHE VERFAHRENSTECHNIK GMBH (DE) | 1981-06-23 | — | — | US | claimed |
| US-4200692-A | Process for the production of xylose by enzymatic hydrolysis of xylan | PROJEKTIERUNG CHEMISCHE VERFAHRENSTECHNIK GMBH (DE) | 1980-04-29 | — | — | US | claimed |
| US-7494589-B2 | Industrial process for food liquids decontamination from chemical and/or biological contaminants | DOX-AL ITALIA S.P.A. (IT) | 2009-02-24 | — | — | US | disclosed |
| US-7101863-B2 | Pharmaceutical compositions with wound healing or anti-complementary activity comprising a dextran derivative | BIODEX (FR) | 2006-09-05 | — | — | US | disclosed |
| US-20050220936-A1 | Industrial process for food liquids decontamination from chemical and/or biological contaminants | DOX-AL ITALIA S.P.A. (IT) | 2005-10-06 | — | — | US | disclosed |
| EP-0990002-B1 | DEXTRAN DERIVATIVES, PREPARATION METHOD AND APPLICATIONS AS MEDICINE WITH SPECIFIC BIOLOGICAL ACTION | BIODEX (FR) | 2005-10-05 | — | — | EP | disclosed |
| US-6946443-B2 | Biomaterial based on an insolubilized dextran derivative and a growth factor | BIODEX (FR) | 2005-09-20 | — | — | US | disclosed |
| US-6646120-B1 | Polysaccharides with side chains of methylcarboxylate, carboxymethylbenzylamide, sulfate and sulfonate groups; use as anti-thrombotic, substitute for plasma and modulator of cell proliferation | BIODEX (FR) | 2003-11-11 | — | — | US | disclosed |
| US-20020183282-A1 | Pharmaceutical compositions with wound healing or anti-complementary activity comprising a dextran derivative | BIODEX (FR) | 2002-12-05 | — | — | US | disclosed |
| US-20020169120-A1 | Biologically active material based on an insolubilised dextran derivative and a growth factor | BIODEX (FR) | 2002-11-14 | — | — | US | disclosed |
| EP-0990002-A1 | DEXTRAN DERIVATIVES, PREPARATION METHOD AND APPLICATIONS AS MEDICINE WITH SPECIFIC BIOLOGICAL ACTION | Solutions (FR) | 2000-04-05 | — | — | EP | disclosed |
| WO-1999029734-A1 | DEXTRAN DERIVATIVES, PREPARATION METHOD AND APPLICATIONS AS MEDICINE WITH SPECIFIC BIOLOGICAL ACTION | SOLUTIONS (FR) | 1999-06-17 | — | — | WO | disclosed |
| US-4621099-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS | USV PHARMACEUTICAL CORPORATION (US) | 1986-11-04 | — | — | US | disclosed |
| US-4275001-A | Process for the manufacture of LH-RH and LH-RH analogs using Glu-His(DnP)-OH | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-06-23 | — | — | US | disclosed |
| US-4200692-A | Process for the production of xylose by enzymatic hydrolysis of xylan | PROJEKTIERUNG CHEMISCHE VERFAHRENSTECHNIK GMBH (DE) | 1980-04-29 | — | — | US | disclosed |