Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 6/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9436866 | 0.89 | CYP1A2 (0.59) | CYP1A2CYP2C9CNR2CNR1MAPK1 | |
| SCHEMBL10752281 | 0.89 | CYP1A2 (0.58) | CYP1A2CYP2C9CNR2CNR1MAPK1 | |
| SCHEMBL4015131 | 0.86 | CYP1A2 (0.61) | CYP1A2CYP2C9CNR2CNR1L3MBTL1 | |
| SCHEMBL4988129 | 0.85 | CYP1A2 (0.56) | CYP1A2CYP2C9MAPK1MEN1KMT2A | |
| SCHEMBL4988124 | 0.84 | CYP1A2 (0.55) | CYP1A2CYP2C9POLBLMNAMEN1 | |
| SCHEMBL31278334 | 0.84 | CYP1A2 (0.59) | CYP1A2CYP2C9L3MBTL1POLBLMNA | |
| SCHEMBL335422 | 0.84 | CYP1A2 (0.59) | CYP1A2CYP2C9L3MBTL1POLBLMNA | |
| SCHEMBL335424 | 0.84 | CYP1A2 (0.61) | CYP1A2CYP2C9MAPK1L3MBTL1POLB | |
| SCHEMBL10516211 | 0.83 | CYP1A2 (0.58) | CYP1A2CYP2C9MEN1KMT2AHIF1A | |
| SCHEMBL7135046 | 0.82 | CYP1A2 (0.54) | CYP1A2CYP2C9POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008279-A | Circulation-active fluoromethoxyphenyl dihydropyridine compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-16 | — | — | US | disclosed |