Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1621078 | 0.87 | CNR2 (0.49) | CNR2CNR1LMNAALDH1A1GAA | |
| SCHEMBL766896 | 0.87 | CNR2 (0.57) | CNR2CNR1MAPK14LMNAMAPT | |
| SCHEMBL1619502 | 0.78 | CNR2 (0.58) | CNR2MAPK14LMNAMAPTMAPK13 | |
| SCHEMBL1621077 | 0.77 | CNR2 (0.57) | CNR2MAPK14LMNAMAPTMAPK13 | |
| SCHEMBL3962960 | 0.77 | CNR2 (0.51) | CNR2CNR1MAPK14LMNAALDH1A1 | |
| SCHEMBL4014179 | 0.76 | CNR2 (0.49) | CNR2MAPK14LMNAALDH1A1MAPT | |
| SCHEMBL4017725 | 0.73 | RAB9A (0.46) | CNR2LMNAALDH1A1MAPT | |
| SCHEMBL12746844 | 0.73 | CNR2 (0.48) | CNR2CNR1MAPK14LMNAMAPT | |
| SCHEMBL1620080 | 0.73 | CNR2 (0.54) | CNR2CNR1LMNAALDH1A1MAPT | |
| SCHEMBL774473 | 0.73 | CNR2 (0.52) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | disclosed |