SCHEMBL4015215

SCHEMBL4015215

O=S(=O)(O)c1coc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 10/20 0.46
CA2 P00918 2/20 0.44
MAOA P21397 3/20 0.42
PTPN1 P18031 1/20 0.42
TTR P02766 1/20 0.40
FTO Q9C0B1 1/20 0.39
RCE1 Q9Y256 1/20 0.39
ADORA2B P29275 1/20 0.38
MIF P14174 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA4 P22748 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
HTR2C P28335 1/20 0.37
TSHR P16473 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MPL P40238 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28047291 0.98 MAOB (0.44) MAOBCA2MAOAPTPN1TTR
SCHEMBL4023068 0.80 CA2 (0.44) MAOBCA2MAOAPTPN1FTO
SCHEMBL29857892 0.80 MAOB (0.44) MAOBCA2MAOAPTPN1FTO
SCHEMBL2087127 0.80 CA2 (0.51) MAOBCA2MAOAPTPN1CA12
SCHEMBL2087967 0.80 MAOB (0.44) MAOBCA2MAOAPTPN1FTO
SCHEMBL15880493 0.79 CA2 (0.44) MAOBCA2MAOAPTPN1FTO
SCHEMBL3796612 0.74 TTR (0.47) MAOBMAOATTRFTO
Hydrochloric Acid SCHEMBL27577221 0.73 TTR (0.46) MAOBMAOATTRFTO
SCHEMBL31678985 0.73 TSHR (0.46) MAOBCA2CA1CA5ATSHR
SCHEMBL31678987 0.72 KDM4E (0.51) MAOBCA2MAOASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3679027-A1 DIHYDROBENZIMIDAZOLONES C4 Therapeutics, Inc. (US) 2020-07-15 EP claimed
WO-2019043217-A1 DIHYDROBENZIMIDAZOLONES F. HOFFMANN-LA ROCHE AG (CH) 2019-03-07 WO claimed
CN-113582978-A 3-thio-benzofuran derivative and synthesis method thereof 齐鲁工业大学 2021-11-02 CN disclosed
CN-110179777-A Medical composition comprising nitroxyl donors 卡尔迪奥克斯尔制药公司 2019-08-30 CN disclosed
CN-105142627-B Pharmaceutical compositions comprising nitroxyl donors 卡尔迪奥克斯尔制药公司 2019-06-21 CN disclosed
CN-105142627-A Pharmaceutical compositions comprising nitroxyl donors CARDIOXYL PHARMACEUTICALS INC 2015-12-09 CN disclosed
CN-104592179-A Preparation method of 3-sulfo benzofuran compound UNIV TIANJIN NORMAL 2015-05-06 CN disclosed
CN-104592179-A Preparation method of 3-sulfo benzofuran compound UNIV TIANJIN NORMAL 2015-05-06 CN disclosed
EP-1085540-B1 SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR PREPARING THE SAME SHOWA DENKO KK (JP) 2009-07-01 EP disclosed
EP-1158551-B1 SOLID ELECTROLYTIC CAPACITOR AND ITS PRODUCTION METHOD SHOWA DENKO KK (JP) 2008-11-19 EP disclosed
EP-1811532-A2 Solid electrolytic capacitor and method for producing the same SHOWA DENKO KABUSHIKI KAISHA (JP) 2007-07-25 EP disclosed
US-6517892-B1 Forming electroconductive film filling microfine pores and covering dielectric layer; oxidative solution polymerization; such as cationic polythiophene or polyfuran SHOWA DENKO K.K. (JP) 2003-02-11 US disclosed
US-6466421-B1 Solid electrolytic capacitor and method for producing the same SHOWA DENKO K.K. (JP) 2002-10-15 US disclosed
US-20020105777-A1 Solid electrolytic capacitor and method for producing the same SHOWA DENKO K.K. 2002-08-08 US disclosed
US-6381121-B1 Solid electrolytic capacitor SHOWA DENKO KABUSHIKI KAISHA (JP) 2002-04-30 US disclosed
EP-1190426-A1 SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR PRODUCING THE SAME Showa Denko K K (JP) 2002-03-27 EP disclosed
US-6344966-B1 ELECTRICALLY CONDUCTING POLYMER LAYER CONTAINS AS A DOPANT AN ANION OF(1) ALKOXY-SUBSTITUTED NAPHTHALENESULFONATE, (2) A HETEROCYCLIC SULFONATE, OR (3) AN ANION OF AN ALIPHATIC POLYCYCLIC COMPOUND SHOWA DENKO K.K. (JP) 2002-02-05 US disclosed
EP-1158551-A1 SOLID ELECTROLYTIC CAPACITOR AND ITS PRODUCTION METHOD Showa Denko K K (JP) 2001-11-28 EP disclosed
EP-1085540-A1 SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR PREPARING THE SAME Showa Denko K K (JP) 2001-03-21 EP disclosed
WO-2000060620-A1 SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR PRODUCING THE SAME SHOWA DENKO K. K. (JP) 2000-10-12 WO disclosed