SCHEMBL4015265

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4017821	0.91	KDR (0.77)	KDRKMT2AMEN1HSD17B10POLB
	SCHEMBL4019386	0.89	KDR (1.00)	KDRKMT2AMEN1HSD17B10POLB
	SCHEMBL4021405	0.86	KDR (0.77)	KDRKMT2AMEN1HSD17B10POLB
	SCHEMBL4017457	0.86	KDR (0.69)	KDRKMT2AMEN1HSD17B10POLB
	SCHEMBL4021231	0.85	KDR (0.76)	KDRKMT2AMEN1HSD17B10POLB
	SCHEMBL4016059	0.84	KDR (0.74)	KDRKMT2AMEN1HSD17B10POLB
	SCHEMBL4016965	0.84	KDR (0.81)	KDRKMT2AMEN1FADS1L3MBTL1
	SCHEMBL4017841	0.84	KDR (0.73)	KDRKMT2AMEN1HSD17B10POLB
	SCHEMBL4020979	0.83	KDR (0.72)	KDRKMT2AMEN1HSD17B10POLB
	SCHEMBL4015093	0.82	KDR (0.78)	KDRKMT2AMEN1HSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.