SCHEMBL4015789

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4023036	0.96	KDR (0.70)	KDRLMNASMN1; SMN2STAT3KMT2A
	SCHEMBL4015769	0.89	KDR (0.72)	KDRSMN1; SMN2KMT2AALDH1A1PKM
	SCHEMBL4017009	0.89	KDR (0.74)	KDRLMNASMN1; SMN2KMT2AALDH1A1
	SCHEMBL4019854	0.87	KDR (0.79)	KDRSMN1; SMN2KMT2AALDH1A1PKM
	SCHEMBL4017529	0.87	KDR (0.69)	KDRSMN1; SMN2KMT2AALDH1A1PKM
	SCHEMBL4017944	0.87	KDR (0.72)	KDRLMNASMN1; SMN2KMT2AKDM4E
	SCHEMBL4015243	0.86	KDR (0.74)	KDRSMN1; SMN2KMT2AALDH1A1PKM
	SCHEMBL4023378	0.86	KDR (0.84)	KDRSMN1; SMN2KMT2AALDH1A1ALOX15
	SCHEMBL4016903	0.85	KDR (0.73)	KDRKMT2AALDH1A1GAAPKM
	SCHEMBL4016715	0.85	KDR (0.79)	KDRLMNASMN1; SMN2KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.