SCHEMBL4017009

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4017456	0.90	KDR (0.67)	KDRPPARGRXFP1NCOR2KMT2A
	SCHEMBL4017944	0.89	KDR (0.72)	KDRPPARGRXFP1NCOR2KMT2A
	SCHEMBL4023378	0.89	KDR (0.84)	KDRKMT2AMAPTMEN1L3MBTL1
	SCHEMBL4021262	0.89	KDR (0.64)	KDRKMT2AMAPTMEN1GAA
	SCHEMBL4015789	0.89	KDR (0.70)	KDRPPARGRXFP1NCOR2KMT2A
	SCHEMBL4023036	0.89	KDR (0.70)	KDRPPARGRXFP1NCOR2KMT2A
	SCHEMBL4016903	0.88	KDR (0.73)	KDRKMT2AMAPTGAAL3MBTL1
	SCHEMBL4019854	0.88	KDR (0.79)	KDRKMT2AMAPTL3MBTL1PKM
	SCHEMBL4016715	0.88	KDR (0.79)	KDRKMT2AMAPTMEN1L3MBTL1
	SCHEMBL4026306	0.88	KDR (0.79)	KDRKMT2AMAPTL3MBTL1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.