Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011596 | 0.91 | PPARG (0.55) | PPARGACHEGRIA2GRIA4AGTR1 | |
| SCHEMBL4016615 | 0.91 | PPARG (0.54) | PPARGACHEGRIA2GRIA4AGTR1 | |
| SCHEMBL4012581 | 0.89 | PPARG (0.59) | PPARGACHEGRIA2GRIA4AGTR1 | |
| SCHEMBL4313411 | 0.89 | PPARG (0.59) | PPARGACHEGRIA2GRIA4AGTR1 | |
| SCHEMBL4012675 | 0.89 | PPARG (0.53) | PPARGACHEGRIA2GRIA4AGTR1 | |
| SCHEMBL1892312 | 0.87 | PPARG (0.58) | PPARGMAPTMAPK1NPSR1AGTR1 | |
| SCHEMBL4019464 | 0.85 | PPARG (0.54) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL4012577 | 0.84 | PPARG (0.57) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL4015645 | 0.84 | PPARG (0.57) | PPARGACHEMAPTMAPK1NPSR1 | |
| SCHEMBL4007590 | 0.84 | PPARG (0.53) | PPARGACHEAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |