SCHEMBL4016153

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4022007	0.89	KDR (0.78)	KDRKMT2APKML3MBTL1LMNA
	SCHEMBL1940864	0.88	KDR (0.57)	KDRTRPV1KMT2APKML3MBTL1
	Hydrochloric Acid SCHEMBL1941344	0.87	KDR (0.56)	KDRTRPV1KMT2APKML3MBTL1
	SCHEMBL1942747	0.87	KDR (0.56)	KDRTRPV1KMT2APKML3MBTL1
	SCHEMBL4018222	0.87	KDR (0.74)	KDRTRPV1KMT2APKML3MBTL1
	SCHEMBL1940906	0.87	KDR (0.55)	KDRTRPV1KMT2APKML3MBTL1
	SCHEMBL4017216	0.86	KDR (0.62)	KDRKMT2APKML3MBTL1LMNA
	SCHEMBL3932884	0.86	KDR (0.55)	KDRTRPV1KMT2APKML3MBTL1
	SCHEMBL4024577	0.86	KDR (0.54)	KDRTRPV1KMT2APKML3MBTL1
	SCHEMBL1940372	0.85	KDR (0.52)	KDRTRPV1KMT2APKML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.