SCHEMBL4017216

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4022007	0.89	KDR (0.78)	KDRKMT2ANPC1TSHRSMN1; SMN2
	SCHEMBL1939568	0.87	KDR (0.56)	KDRKMT2ANPC1SMN1; SMN2TP53
	SCHEMBL4015243	0.87	KDR (0.74)	KDRKMT2ANPC1SMN1; SMN2TP53
	SCHEMBL4016153	0.86	KDR (0.62)	KDRKMT2ASMN1; SMN2PKML3MBTL1
	SCHEMBL4022328	0.85	KDR (0.60)	KDRKMT2ANPC1SMN1; SMN2TP53
	SCHEMBL4015968	0.85	KDR (0.60)	KDRKMT2ASMN1; SMN2TP53PKM
	SCHEMBL4018128	0.83	KDR (0.58)	KDRKMT2ASMN1; SMN2TP53PKM
	SCHEMBL4023689	0.83	KDR (0.62)	KDRKMT2ANPC1SMN1; SMN2LMNA
	SCHEMBL4019866	0.83	KDR (0.57)	KDRKMT2ANPC1SMN1; SMN2TP53
	SCHEMBL4017260	0.83	KDR (0.60)	KDRKMT2ASMN1; SMN2TP53PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.