Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 6/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.36 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.36 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | SLC33A1 | O00400 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1886920 | 0.91 | AGTR1 (0.37) | GNRHREEDRBBP4SUZ12EZH2 | |
| SCHEMBL4013058 | 0.89 | PPARG (0.46) | AGTR1AGTR2PPARGACHE | |
| SCHEMBL4011357 | 0.86 | AGTR1 (0.40) | AGTR1AGTR2PPARGACHE | |
| SCHEMBL14207794 | 0.84 | GNRHR (0.36) | GNRHREEDRBBP4SUZ12EZH2 | |
| SCHEMBL1897246 | 0.80 | PPARG (0.47) | AGTR1PPARGACHE | |
| SCHEMBL4012701 | 0.78 | PPARG (0.51) | AGTR1AGTR2PPARGACHEFABP4 | |
| SCHEMBL12348686 | 0.77 | SLC33A1 (0.38) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL1888339 | 0.77 | PPARG (0.50) | AGTR1PPARGSLC33A1 | |
| SCHEMBL12348764 | 0.77 | SLC33A1 (0.38) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL1891328 | 0.77 | AGTR1 (0.43) | AGTR1AGTR2PPARGACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |