SCHEMBL4016774

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18049801	0.91	KDR (0.64)	KDRKMT2AEGLN1ALDH1A1CYP2C9
	SCHEMBL4023037	0.91	KDR (0.67)	KDRKMT2AFLT1ABL1EGFR
	SCHEMBL4017094	0.90	KDR (0.66)	KDRKMT2AFLT1ABL1EGFR
	SCHEMBL4018222	0.90	KDR (0.74)	KDRKMT2AFLT1NAMPTALDH1A1
	SCHEMBL4023378	0.90	KDR (0.84)	KDRKMT2AJAK2TYK2ALDH1A1
	SCHEMBL4019833	0.89	KDR (0.79)	KDRKMT2ANAMPTALDH1A1CYP2C9
	SCHEMBL4020476	0.88	KDR (0.72)	KDRKMT2AALDH1A1CYP2C9SMN1; SMN2
	SCHEMBL4017671	0.88	KDR (0.62)	KDRKMT2AFLT1ABL1EGFR
	SCHEMBL1939653	0.88	KDR (0.59)	KDRKMT2AEGLN1FLT1ABL1
	SCHEMBL4019429	0.87	KDR (0.81)	KDRKMT2AALDH1A1CYP2C9SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.