SCHEMBL4019833

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4023378	0.92	KDR (0.84)	KDRKMT2ACYP2C9ALDH1A1L3MBTL1
	SCHEMBL4018819	0.90	KDR (0.71)	KDRKMT2ACYP2C9LMNAALDH1A1
	SCHEMBL4019429	0.89	KDR (0.81)	KDRKMT2ACYP2C9LMNAALDH1A1
	SCHEMBL4019980	0.89	KDR (0.80)	KDRKMT2ACYP2C9LMNAALDH1A1
	SCHEMBL18049801	0.89	KDR (0.64)	KDRKMT2ACYP2C9LMNACYP3A4
	SCHEMBL4016774	0.89	KDR (0.76)	KDRKMT2ACYP2C9ALDH1A1L3MBTL1
	SCHEMBL4022509	0.88	KDR (0.79)	KDRKMT2ACYP2C9CYP3A4CYP2C19
	SCHEMBL4023386	0.88	KDR (0.79)	KDRKMT2ACYP2C9ALDH1A1L3MBTL1
	SCHEMBL4019854	0.88	KDR (0.79)	KDRKMT2ACYP2C9ALDH1A1L3MBTL1
	SCHEMBL4016715	0.88	KDR (0.79)	KDRKMT2ACYP2C9LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.