⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3062512 | 1.00 | — | — | |
| SCHEMBL169924 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL27867698 | 0.97 | — | — | |
| SCHEMBL6929559 | 0.97 | — | — | |
| SCHEMBL27566442 | 0.97 | — | — | |
| SCHEMBL6928458 | 0.97 | — | — | |
| SCHEMBL27849642 | 0.97 | — | — | |
| SCHEMBL6930365 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL27831159 | 0.97 | — | — | |
| SCHEMBL6930375 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586616-B1 | Cyanation and esterification of 3,4-epoxybutyric acid sodium salts to form chemical intermediates for antilipemic agents; by-product inhibition | SAMSUNG FINE CHEMICALS CO., LTD. (KR) | 2003-07-01 | — | — | US | claimed |
| EP-1149068-A4 | A PROCESS FOR PREPARING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER | SAMSUNG FINE CHEMICALS CO LTD (KR) | 2003-01-02 | — | — | EP | claimed |
| EP-1109797-B1 | PROCESS FOR MANUFACTURING AN OPTICALLY ACTIVE (S)-3,4-EPOXYBUTYRIC ACID SALT | SAMSUNG FINE CHEMICALS CO LTD (KR) | 2002-03-27 | — | — | EP | claimed |
| EP-1149068-A1 | A PROCESS FOR PREPARING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER | Samsung Fine Chemicals Co., Ltd. (KR) | 2001-10-31 | — | — | EP | claimed |
| US-6284902-B1 | Process for manufacturing an optically active (S)-3,4-epoxybutyric acid salt | SAMSUNG FINE CHEMICALS CO., LTD. (KR) | 2001-09-04 | — | — | US | claimed |
| EP-1109797-A1 | PROCESS FOR MANUFACTURING AN OPTICALLY ACTIVE (S)-3,4-EPOXYBUTYRIC ACID SALT | Samsung Fine Chemicals Co., Ltd. (KR) | 2001-06-27 | — | — | EP | claimed |
| WO-2000046186-A1 | A PROCESS FOR PREPARING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER | SAMSUNG FINE CHEMICALS CO., LTD (KR) | 2000-08-10 | — | — | WO | claimed |
| WO-2000005227-A1 | PROCESS FOR MANUFACTURING AN OPTICALLY ACTIVE (S)-3,4-EPOXYBUTYRIC ACID SALT | SAMSUNG FINE CHEMICALS CO., LTD. (KR) | 2000-02-03 | — | — | WO | claimed |
| EP-0430096-B1 | Process for the production of 3,4-epoxybutyrate and intermediate therefor | KANEGAFUCHI CHEMICAL IND (JP) | 1994-03-02 | — | — | EP | claimed |
| US-5248601-A | Amination of epoxybutyric ester and hydrolysis | FRANCALANCI FRANCO (IT) | 1993-09-28 | — | — | US | claimed |
| EP-0237080-B1 | PROCESS FOR THE PREPARATION OF L(-)-CARNITINE CHLORIDE STARTING FROM 3,4-EPOXYBUTYRIC ESTERS | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1992-06-03 | — | — | EP | claimed |
| EP-0237983-B1 | PROCESS FOR THE BIOTECHNOLOGICAL PREPARATION OF L (-)-CARNITINE CHLORIDE | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1992-05-20 | — | — | EP | claimed |
| EP-0430096-A2 | Process for the production of 3,4-epoxybutyrate and intermediate therefor | Kanegafuchi Chemical Industry Co., Ltd. (JP) | 1991-06-05 | — | — | EP | claimed |
| US-4865771-A | SELECTIVELY HYDROLYZING ESTER WITH ENZYME, SEPARATING ENANTIOMORPHS, REACTING WITH TRIMETHYLAMINE HYDROCHLORIDE, HYDROLYZING | ISTITUTO GUIDO DONEGANI S.P.A. (IT) | 1989-09-12 | — | — | US | claimed |
| EP-0237983-A2 | Process for the biotechnological preparation of L (-)-carnitine chloride | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1987-09-23 | — | — | EP | claimed |
| EP-0237080-A2 | Process for the preparation of L(-)-carnitine chloride starting from 3,4-epoxybutyric esters | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1987-09-16 | — | — | EP | claimed |
| US-20250042878-A1 | INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMA (US) | 2025-02-06 | — | — | US | disclosed |
| CN-105132488-A | Preparation method of -4-cyano-3-hydroxy ethyl butyrate | UNIV JIANGSU TECHNOLOGY | 2015-12-09 | — | — | CN | disclosed |
| EP-0237080-A2 | Process for the preparation of L(-)-carnitine chloride starting from 3,4-epoxybutyric esters | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1987-09-16 | — | — | EP | disclosed |
| EP-0237080-A2 | Process for the preparation of L(-)-carnitine chloride starting from 3,4-epoxybutyric esters | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1987-09-16 | — | — | EP | disclosed |