Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.50 |
| ▸ | TGM2 | P21980 | 5/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | SPR | P35270 | 1/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4809284 | 0.92 | KMT2A (0.53) | KMT2AATMHDAC3HDAC4HDAC1 | |
| SCHEMBL4296790 | 0.90 | HDAC3 (0.61) | KMT2AATMHDAC3HDAC4HDAC1 | |
| SCHEMBL14164254 | 0.81 | HDAC1 (0.64) | KMT2AATMHDAC3HDAC4HDAC1 | |
| SCHEMBL29437927 | 0.78 | KMT2A (0.88) | KMT2AATMTGM2MMP2MMP9 | |
| SCHEMBL25531 | 0.78 | KMT2A (0.88) | KMT2AATMTGM2MMP2MMP9 | |
| SCHEMBL27571758 | 0.76 | KMT2A (0.71) | KMT2AATMTGM2MMP2MMP9 | |
| SCHEMBL5319421 | 0.76 | HDAC3 (0.80) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28919033 | 0.76 | HDAC3 (0.58) | KMT2AATMHDAC3HDAC4HDAC1 | |
| SCHEMBL28919064 | 0.75 | HDAC3 (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL18711519 | 0.74 | KMT2A (0.71) | KMT2AATMTGM2MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009089598-A2 | MSMB-GENE METHYLATION BASED DIAGNOSIS, STAGING AND PROGNOSIS OF PROSTATE CANCER | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2009-07-23 | — | — | WO | disclosed |