SCHEMBL29437927

SCHEMBL29437927

CN(C)c1cccc2c(S(=O)(=O)N3CC3)cccc12

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.88
ATM Q13315 1/20 0.88
SMN1; SMN2 Q16637 1/20 0.62
CA2 P00918 1/20 0.61
TGM2 P21980 5/20 0.61
CYP1A2 P05177 1/20 0.55
CYP2C19 P33261 1/20 0.55
HTT P42858 1/20 0.55
HIF1A Q16665 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
HTR6 P50406 1/20 0.55
MMP2 P08253 1/20 0.53
MMP9 P14780 1/20 0.53
F2 P00734 1/20 0.52
PRSS1 P07477 1/20 0.52
PRSS2 P07478 1/20 0.52
PRSS3 P35030 1/20 0.52
EDNRA P25101 3/20 0.50
POLB P06746 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25531 1.00 KMT2A (0.88) KMT2AATMSMN1; SMN2CA2TGM2
SCHEMBL15934204 0.94 KMT2A (0.79) KMT2AATMSMN1; SMN2CA2TGM2
SCHEMBL14256516 0.92 KMT2A (0.75) KMT2AATMSMN1; SMN2CA2TGM2
SCHEMBL14266719 0.90 KMT2A (0.73) KMT2AATMSMN1; SMN2CA2TGM2
SCHEMBL5650140 0.90 KMT2A (0.77) KMT2AATMSMN1; SMN2CA2TGM2
SCHEMBL31033068 0.90 KMT2A (0.77) KMT2AATMSMN1; SMN2CA2TGM2
SCHEMBL27571758 0.89 KMT2A (0.71) KMT2AATMSMN1; SMN2CA2TGM2
SCHEMBL18711519 0.89 KMT2A (0.71) KMT2AATMSMN1; SMN2CA2TGM2
SCHEMBL18138090 0.89 KMT2A (0.75) KMT2AATMSMN1; SMN2CA2TGM2
SCHEMBL19856464 0.89 KMT2A (0.75) KMT2AATMSMN1; SMN2CA2TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12584915-B2 Glyphosate biosensor THE TRUSTEES OF INDIANA UNIVERSITY (US) 2026-03-24 US claimed
US-20220276241-A1 GLYPHOSATE BIOSENSOR THE TRUSTEES OF INDIANA UNIVERSITY 2022-09-01 US claimed
EP-4007767-A1 GLYPHOSATE BIOSENSOR The Trustees of Indiana University (US) 2022-06-08 EP claimed
US-12584915-B2 Glyphosate biosensor THE TRUSTEES OF INDIANA UNIVERSITY (US) 2026-03-24 US disclosed
EP-3515928-B1 UNSTRUCTURED NON-REPETITIVE POLYPEPTIDES HAVING LCST BEHAVIOR UNIV DUKE (US) 2026-01-28 EP disclosed
US-12084480-B2 Unstructured non-repetitive polypeptides having lcst behavior DUKE UNIVERSITY (US) 2024-09-10 US disclosed
US-20230086188-A1 PROTEINS WITH PREDICTABLE LIQUID-LIQUID PHASE SEPARATION UNIV DUKE (US) 2023-03-23 US disclosed
US-20230093708-A1 PROTEIN NANOPARTICLE DESIGN AND APPLICATION DUKE UNIVERSITY 2023-03-23 US disclosed
US-11554097-B2 Recombinant production of hybrid lipid-biopolymer materials that self-assemble and encapsulate agents DUKE UNIVERSITY (US) 2023-01-17 US disclosed
US-20220411847-A1 GLUCOSE/GALACTOSE BIOSENSORS AND METHODS OF USING SAME UNIV DUKE (US) 2022-12-29 US disclosed
EP-4087856-A2 PROTEINS WITH PREDICTABLE LIQUID-LIQUID PHASE SEPARATION Duke University (US) 2022-11-16 EP disclosed
EP-4087616-A1 PROTEIN NANOPARTICLE DESIGN AND APPLICATION Duke University (US) 2022-11-16 EP disclosed
US-11458205-B2 Genetically encoded intrinsically disordered stealth polymers for delivery and methods of using same DUKE UNIVERSITY (US) 2022-10-04 US disclosed
US-20220276241-A1 GLYPHOSATE BIOSENSOR THE TRUSTEES OF INDIANA UNIVERSITY 2022-09-01 US disclosed
EP-4007767-A1 GLYPHOSATE BIOSENSOR The Trustees of Indiana University (US) 2022-06-08 EP disclosed
US-11352657-B2 Glucose/galactose biosensors and methods of using same DUKE UNIVERSITY (US) 2022-06-07 US disclosed
US-11291997-B2 Rotary manifold for paper-based immunoassays COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2022-04-05 US disclosed
US-20220098248-A1 UNSTRUCTURED NON-REPETITIVE POLYPEPTIDES HAVING LCST BEHAVIOR DUKE UNIVERSITY 2022-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584915-B2 Glyphosate biosensor TMIGD3, BTD, PTMS KMT2A 3387/4885ATM 72/4885SMN1; SMN2 4301/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.