SCHEMBL4016896

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4019790	0.86	KDR (0.62)	KDRALDH1A1CYP2C9PKML3MBTL1
	SCHEMBL4017679	0.85	KDR (0.71)	KDRALDH1A1CYP2C9PKML3MBTL1
	SCHEMBL4017427	0.83	KDR (0.62)	KDRALDH1A1CYP2C9L3MBTL1KMT2A
	SCHEMBL4017840	0.83	KDR (0.61)	KDRALDH1A1CYP2C9PKML3MBTL1
	SCHEMBL4019980	0.82	KDR (0.80)	KDRALDH1A1CYP2C9PKML3MBTL1
	SCHEMBL4020312	0.82	KDR (0.63)	KDRALDH1A1CYP2C9PKML3MBTL1
	SCHEMBL4023378	0.82	KDR (0.84)	KDRALDH1A1CYP2C9PKML3MBTL1
	SCHEMBL4021565	0.82	KDR (0.60)	KDRALDH1A1CYP2C9PKML3MBTL1
	SCHEMBL4015452	0.81	KDR (0.62)	KDRALDH1A1CYP2C9PKML3MBTL1
	SCHEMBL4023386	0.80	KDR (0.79)	KDRALDH1A1CYP2C9PKML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.