SCHEMBL4017840

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4021565	0.91	KDR (0.60)	KDRMAPTKMT2AMEN1HTT
	SCHEMBL4018659	0.85	KDR (0.61)	KDRMAPTKMT2AMEN1HTT
	SCHEMBL4017679	0.84	KDR (0.71)	KDRKMT2AMEN1HTTL3MBTL1
	SCHEMBL4023756	0.83	KDR (0.64)	KDRMAPTKMT2AMEN1HTT
	SCHEMBL4018587	0.83	LMNA (0.70)	KDRMAPTKMT2AMEN1HTT
	SCHEMBL4017456	0.83	KDR (0.67)	KDRMAPTKMT2AMEN1L3MBTL1
	SCHEMBL4016896	0.83	KDR (0.63)	KDRMAPTKMT2AMEN1HTT
	SCHEMBL4015452	0.82	KDR (0.62)	KDRMAPTKMT2AHTTL3MBTL1
	SCHEMBL4019790	0.82	KDR (0.62)	KDRMAPTKMT2AMEN1HTT
	SCHEMBL4017009	0.82	KDR (0.74)	KDRMAPTKMT2AMEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.