SCHEMBL4016952

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11187836	0.93	GSK3B (0.58)	POLBSMN1; SMN2HPGDCYP1A2CYP3A4
	SCHEMBL11961686	0.85	KMT2A (0.59)	POLBSMN1; SMN2HPGDCYP1A2CYP3A4
	SCHEMBL3888099	0.84	HPGD (0.61)	POLBSMN1; SMN2HPGDCYP1A2CYP2C9
	SCHEMBL16152812	0.83	CYP1A2 (0.50)	POLBSMN1; SMN2HPGDCYP1A2CYP3A4
	SCHEMBL4016992	0.81	APEX1 (0.58)	POLBSMN1; SMN2HPGDCYP1A2CYP3A4
	SCHEMBL3761131	0.81	CA12 (0.57)	POLBSMN1; SMN2HPGDMEN1KMT2A
	SCHEMBL2705369	0.81	CA12 (0.57)	POLBSMN1; SMN2HPGDMEN1KMT2A
	SCHEMBL509527	0.80	HPGD (0.61)	POLBSMN1; SMN2HPGDCYP1A2CYP2C9
	SCHEMBL1832304	0.80	HAO1 (0.54)	POLBCYP1A2CYP3A4CYP2D6CYP2C9
	SCHEMBL3889931	0.79	MAOB (0.54)	POLBSMN1; SMN2HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.