SCHEMBL4016992

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3889076	0.87	APEX1 (0.65)	APEX1CYP1A2CYP2C9HPGDHSD17B10
	SCHEMBL30198674	0.87	APEX1 (0.65)	APEX1CYP1A2CYP2C9HPGDHSD17B10
	SCHEMBL12581571	0.84	APEX1 (0.65)	APEX1CYP1A2CYP2C9HPGDHSD17B10
	SCHEMBL15819764	0.82	SIRT2 (0.58)	APEX1CYP1A2CYP2C9HPGDHSD17B10
	SCHEMBL4016952	0.81	POLB (0.57)	CYP1A2CYP2C9HPGDHSD17B10SMN1; SMN2
	SCHEMBL15819770	0.81	SIRT2 (0.59)	APEX1CYP1A2CYP2C9HPGDHSD17B10
	SCHEMBL15818934	0.78	MRGPRX4 (0.57)	APEX1CYP1A2CYP2C9HPGDHSD17B10
	SCHEMBL18552643	0.78	APEX1 (0.54)	APEX1CYP1A2CYP2C9HPGDHSD17B10
	SCHEMBL13802466	0.78	MRGPRX4 (0.63)	APEX1CYP1A2CYP2C9HPGDHSD17B10
	SCHEMBL6347118	0.78	SMN1; SMN2 (0.60)	APEX1CYP1A2CYP2C9HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.