SCHEMBL4017151

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4016597	0.88	KDR (1.00)	KDRNPC1TSHRALDH1A1CYP2C9
	SCHEMBL4017982	0.86	KDR (0.59)	KDRNPC1ALDH1A1CYP2C9PKM
	SCHEMBL4019641	0.84	KDR (0.56)	KDRNPC1ALDH1A1CYP2C9PKM
	SCHEMBL4023718	0.84	KDR (0.55)	KDRNPC1ALDH1A1CYP2C9PKM
	SCHEMBL4016786	0.84	KDR (0.56)	KDRALDH1A1CYP2C9PKML3MBTL1
	SCHEMBL4021015	0.84	KDR (0.56)	KDRNPC1ALDH1A1CYP2C9PKM
	SCHEMBL4018015	0.83	KDR (0.76)	KDRNPC1TSHRALDH1A1CYP2C9
	SCHEMBL4022007	0.83	KDR (0.78)	KDRNPC1TSHRALDH1A1CYP2C9
	SCHEMBL15314445	0.82	KDR (0.54)	KDRALDH1A1CYP2C9PKML3MBTL1
	SCHEMBL4021297	0.82	KDR (0.53)	KDRALDH1A1CYP2C9PKML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.