SCHEMBL4017982

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4018222	0.89	KDR (0.74)	KDRPKML3MBTL1KMT2AALDH1A1
	SCHEMBL4017151	0.86	KDR (0.78)	KDRPKML3MBTL1KMT2AALDH1A1
	SCHEMBL4019641	0.84	KDR (0.56)	KDRPKML3MBTL1KMT2AALDH1A1
	SCHEMBL4023718	0.83	KDR (0.55)	KDRPKML3MBTL1KMT2AALDH1A1
	SCHEMBL4021015	0.83	KDR (0.56)	KDRPKML3MBTL1KMT2AALDH1A1
	SCHEMBL13167594	0.82	KMT2A (0.53)	KDRKMT2ATRPV1NAMPT
	SCHEMBL1940864	0.82	KDR (0.57)	KDRPKML3MBTL1KMT2AALDH1A1
	SCHEMBL4016153	0.82	KDR (0.62)	KDRPKML3MBTL1KMT2AALDH1A1
	SCHEMBL15314445	0.82	KDR (0.54)	KDRPKML3MBTL1KMT2AALDH1A1
	SCHEMBL4021297	0.82	KDR (0.53)	KDRPKML3MBTL1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.