Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 18/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 15/20 | 0.63 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017349 | 1.00 | CHRM3 (0.63) | CHRM3ADRB2ADRB3 | |
| Hydrochloric Acid SCHEMBL11669931 | 0.86 | ADRB3 (0.71) | ADRB2ADRB3 | |
| SCHEMBL11747553 | 0.86 | ADRB3 (0.74) | ADRB2ADRB3 | |
| Hydrochloric Acid SCHEMBL11744017 | 0.85 | ADRB3 (0.72) | ADRB2ADRB3 | |
| SCHEMBL4018079 | 0.83 | CHRM3 (0.49) | CHRM3ADRB2 | |
| SCHEMBL4018077 | 0.83 | CHRM3 (0.49) | CHRM3ADRB2 | |
| SCHEMBL11669746 | 0.79 | ADRB3 (0.60) | ADRB2ADRB3 | |
| SCHEMBL3136753 | 0.78 | ADRB3 (0.72) | ADRB2ADRB3 | |
| SCHEMBL4995820 | 0.78 | CHRM3 (0.72) | CHRM3ADRB2 | |
| SCHEMBL4995831 | 0.78 | CHRM3 (0.72) | CHRM3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074094-A1 | SULFONAMIDE DERIVATIVES AS ADRENERGIC AGONISTS AND MUSCARINIC ANTAGONISTS | Pfizer Limited (GB) | 2009-07-01 | — | — | EP | claimed |
| WO-2008041095-A1 | SULFONAMIDE DERIVATIVES AS ADRENERGIC AGONISTS AND MUSCARINIC ANTAGONISTS | PFIZER LIMITED (GB) | 2008-04-10 | — | — | WO | claimed |
| EP-2074094-A1 | SULFONAMIDE DERIVATIVES AS ADRENERGIC AGONISTS AND MUSCARINIC ANTAGONISTS | Pfizer Limited (GB) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008041095-A1 | SULFONAMIDE DERIVATIVES AS ADRENERGIC AGONISTS AND MUSCARINIC ANTAGONISTS | PFIZER LIMITED (GB) | 2008-04-10 | — | — | WO | disclosed |