Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 20/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 17/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018077 | 1.00 | CHRM3 (0.49) | CHRM3ADRB2 | |
| SCHEMBL4018273 | 0.85 | CHRM3 (0.40) | CHRM3ADRB2 | |
| SCHEMBL4018275 | 0.85 | CHRM3 (0.40) | CHRM3ADRB2 | |
| SCHEMBL4017344 | 0.83 | CHRM3 (0.63) | CHRM3ADRB2 | |
| SCHEMBL4017349 | 0.83 | CHRM3 (0.63) | CHRM3ADRB2 | |
| SCHEMBL4995539 | 0.81 | CHRM3 (0.59) | CHRM3ADRB2 | |
| SCHEMBL4995531 | 0.81 | CHRM3 (0.59) | CHRM3ADRB2 | |
| SCHEMBL4996550 | 0.81 | CHRM3 (0.59) | CHRM3ADRB2 | |
| SCHEMBL4996537 | 0.81 | CHRM3 (0.59) | CHRM3ADRB2 | |
| SCHEMBL4989735 | 0.78 | CHRM3 (0.59) | CHRM3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074094-A1 | SULFONAMIDE DERIVATIVES AS ADRENERGIC AGONISTS AND MUSCARINIC ANTAGONISTS | Pfizer Limited (GB) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008041095-A1 | SULFONAMIDE DERIVATIVES AS ADRENERGIC AGONISTS AND MUSCARINIC ANTAGONISTS | PFIZER LIMITED (GB) | 2008-04-10 | — | — | WO | disclosed |