Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 13/20 | 0.71 |
| ▸ | S1PR3 | Q99500 | 9/20 | 0.71 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.71 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL386642 | 0.97 | S1PR1 (0.67) | S1PR1S1PR3S1PR5S1PR4MAPT | |
| SCHEMBL4017370 | 0.94 | S1PR1 (0.62) | S1PR1S1PR3S1PR5MAPTKMT2A | |
| SCHEMBL4015784 | 0.90 | S1PR1 (0.81) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL386170 | 0.88 | S1PR1 (0.84) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL383311 | 0.87 | S1PR1 (0.51) | S1PR1S1PR3S1PR5MAPTKMT2A | |
| SCHEMBL385439 | 0.85 | S1PR1 (0.51) | S1PR1S1PR3S1PR5S1PR4MAPT | |
| SCHEMBL386701 | 0.85 | S1PR1 (0.79) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL385675 | 0.85 | S1PR1 (0.79) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL386292 | 0.84 | S1PR1 (0.81) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL383528 | 0.84 | S1PR1 (0.48) | S1PR1S1PR3S1PR5MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471054-B1 | AMINO ALCOHOL DERIVATIVE OR PHOSPHONIC ACID DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THESE | DAIICHI SANKYO CO LTD (JP) | 2009-07-01 | — | — | EP | claimed |