Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.62 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.62 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017372 | 0.94 | S1PR1 (0.71) | S1PR1S1PR3S1PR5MAPTKMT2A | |
| SCHEMBL386642 | 0.92 | S1PR1 (0.67) | S1PR1S1PR3S1PR5MAPTKMT2A | |
| SCHEMBL4015779 | 0.89 | S1PR1 (0.71) | S1PR1S1PR3S1PR5HDAC1HDAC8 | |
| SCHEMBL383311 | 0.87 | S1PR1 (0.51) | S1PR1S1PR3S1PR5MAPTKMT2A | |
| SCHEMBL383528 | 0.85 | S1PR1 (0.48) | S1PR1S1PR3S1PR5MAPTKMT2A | |
| SCHEMBL385439 | 0.84 | S1PR1 (0.51) | S1PR1S1PR3S1PR5MAPTKMT2A | |
| SCHEMBL4016195 | 0.84 | S1PR1 (0.71) | S1PR1S1PR3S1PR5 | |
| SCHEMBL4019428 | 0.84 | S1PR1 (0.73) | S1PR1S1PR3S1PR5 | |
| SCHEMBL4015784 | 0.83 | S1PR1 (0.81) | S1PR1S1PR3S1PR5 | |
| SCHEMBL4015886 | 0.81 | S1PR1 (0.72) | S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471054-B1 | AMINO ALCOHOL DERIVATIVE OR PHOSPHONIC ACID DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THESE | DAIICHI SANKYO CO LTD (JP) | 2009-07-01 | — | — | EP | claimed |