SCHEMBL4017609

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4019414	0.91	KDR (0.71)	KDRKMT2ARAB9ANPC1ALDH1A1
	SCHEMBL4019866	0.88	KDR (0.57)	KDRKMT2ARAB9ANPC1LMNA
	SCHEMBL4021089	0.88	KDR (0.70)	KDRKMT2AALDH1A1LMNATP53
	SCHEMBL4017015	0.88	KDR (0.74)	KDRKMT2AALDH1A1LMNAMAPT
	SCHEMBL4023085	0.87	KDR (0.69)	KDRKMT2ARAB9ANPC1ALDH1A1
	SCHEMBL4021583	0.86	KDR (0.65)	KDRKMT2AALDH1A1LMNATP53
	SCHEMBL4020489	0.86	KDR (0.67)	KDRKMT2AALDH1A1LMNAKDM4E
	SCHEMBL4019595	0.86	KDR (0.74)	KDRKMT2ARAB9ANPC1ALDH1A1
	SCHEMBL4022400	0.85	KDR (0.66)	KDRKMT2ARAB9ANPC1ALDH1A1
	SCHEMBL4020907	0.85	KDR (0.64)	KDRKMT2ARAB9ANPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.