SCHEMBL4020907

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4016130	0.89	KDR (0.68)	KDRKMT2ALMNAFLT1ABL1
	SCHEMBL4017534	0.89	KDR (0.64)	KDRKMT2AFLT1ABL1EGFR
	SCHEMBL4017759	0.89	KDR (0.70)	KDRKMT2AMEN1NPSR1TMPRSS4
	SCHEMBL4024905	0.86	KDR (0.61)	KDRMAPTKMT2ALMNANPSR1
	SCHEMBL4019912	0.86	KDR (0.61)	KDRMAPTKMT2AFLT1ABL1
	SCHEMBL4018538	0.85	KDR (0.60)	KDRMAPTKMT2AMEN1LMNA
	SCHEMBL4017609	0.85	KDR (0.67)	KDRMAPTKMT2AMEN1LMNA
	SCHEMBL4016774	0.85	KDR (0.76)	KDRKMT2AFLT1ABL1EGFR
	SCHEMBL4023108	0.84	KDR (0.61)	KDRMAPTKMT2AMEN1LMNA
	SCHEMBL4017094	0.84	KDR (0.66)	KDRMAPTKMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.