SCHEMBL4017616

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4022548	0.90	KDR (0.57)	KDRNPC1KITBRAFKDM4E
	SCHEMBL4024577	0.88	KDR (0.54)	KDRKITBRAFLMNAKMT2A
	SCHEMBL4022007	0.87	KDR (0.78)	KDRNPC1TSHRKDM4ELMNA
	SCHEMBL4017799	0.86	KDR (0.52)	KDRNPC1KITBRAFKDM4E
	SCHEMBL4017925	0.86	KDR (0.53)	KDRNPC1KITBRAFSMN1; SMN2
	SCHEMBL4019821	0.86	KDR (0.52)	KDRKITBRAFKDM4ELMNA
	SCHEMBL1941144	0.85	KDR (0.75)	KDRNPC1TSHRKDM4ELMNA
	SCHEMBL1939717	0.85	KDR (0.75)	KDRNPC1TSHRKDM4ELMNA
	SCHEMBL4019807	0.85	KDR (0.50)	KDRKITBRAFKDM4ELMNA
	SCHEMBL15314456	0.85	KDR (0.51)	KDRKITBRAFKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.