SCHEMBL4022548

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4017616	0.90	KDR (0.71)	KDRALDH1A1KITBRAFSMN1; SMN2
	SCHEMBL4019807	0.89	KDR (0.50)	KDRALDH1A1KITBRAFSMN1; SMN2
	SCHEMBL4023689	0.87	KDR (0.62)	KDRGRM4HDAC6ALDH1A1SMN1; SMN2
	SCHEMBL4019811	0.85	KDR (0.78)	KDRGRM4HDAC6ALDH1A1SMN1; SMN2
	Hydrochloric Acid SCHEMBL1941498	0.85	KDR (0.59)	KDRGRM4HDAC6ALDH1A1SMN1; SMN2
	SCHEMBL4017799	0.85	KDR (0.52)	KDRALDH1A1KITBRAFSMN1; SMN2
	SCHEMBL4019821	0.84	KDR (0.52)	KDRGRM4ALDH1A1KITBRAF
	SCHEMBL1942002	0.84	KDR (0.58)	KDRGRM4HDAC6ALDH1A1KIT
	SCHEMBL1939754	0.83	KDR (0.57)	KDRGRM4HDAC6ALDH1A1KIT
	SCHEMBL4017247	0.83	KDR (0.50)	KDRALDH1A1KITBRAFSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.