SCHEMBL4017623

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4020008	0.83	LOXL2 (0.44)	GABRA5LOXL2LOXGABRPGABRD
	SCHEMBL4018107	0.83	LOXL2 (0.59)	LOXL2LOXACACB
	SCHEMBL3127292	0.79	TSHR (0.64)	TSHRMAOBALDH1A1MAPTMAPK1
	SCHEMBL4019820	0.78	LOXL2 (0.41)	GABRA5MAPK14LOXL2LOXCYP2D6
	SCHEMBL28272115	0.77	MAOB (0.63)	MAOB
	SCHEMBL5554530	0.76	RECQL (0.46)	GABRA5PKMMAPK14LOXL2LOX
	SCHEMBL4927819	0.76	LOXL2 (0.66)	GABRA5MAPK14LOXL2LOXMAOB
	SCHEMBL30931622	0.76	LOXL2 (0.66)	GABRA5MAPK14LOXL2LOXMAOB
	SCHEMBL30825708	0.75	MAOB (0.60)	GABRA5MAOBALDH1A1ABCB1
	Hydrochloric Acid SCHEMBL4018838	0.75	LOXL2 (0.46)	GABRA5MAPK14LOXL2LOXTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.