SCHEMBL4017626

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4020492	0.86	KDR (0.71)	EGLN1KMT2AKDRALDH1A1TP53
	SCHEMBL1943033	0.85	EGLN1 (0.50)	EGLN1KMT2APKML3MBTL1ALDH1A1
	SCHEMBL4017009	0.84	KDR (0.74)	KMT2AKDRPKML3MBTL1ALDH1A1
	SCHEMBL1788040	0.83	EGLN1 (0.54)	EGLN1KMT2AALDH1A1RXFP1TP53
	SCHEMBL2911170	0.83	KMT2A (0.53)	EGLN1KMT2AALDH1A1RXFP1TP53
	SCHEMBL1943157	0.82	EGLN1 (0.47)	EGLN1KMT2AALDH1A1RXFP1TP53
	SCHEMBL449175	0.80	KMT2A (0.59)	EGLN1KMT2AKDRALDH1A1LMNA
	SCHEMBL4018030	0.80	KDR (0.56)	KMT2AKDRPKML3MBTL1ALDH1A1
	SCHEMBL4017456	0.79	KDR (0.67)	EGLN1KMT2AKDRPKML3MBTL1
	SCHEMBL11812817	0.79	KMT2A (0.63)	EGLN1KMT2AALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.