Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4012027 | 0.93 | PPARG (0.63) | PPARGACHEALDH1A1MAPK1 | |
| SCHEMBL4012581 | 0.90 | PPARG (0.59) | PPARGESR2ACHE | |
| SCHEMBL1890122 | 0.88 | PPARG (0.61) | PPARGESR2ACHE | |
| SCHEMBL4010868 | 0.87 | PPARG (0.55) | PPARGACHEALDH1A1MAPK1 | |
| SCHEMBL4009715 | 0.85 | PPARG (0.53) | PPARGACHE | |
| SCHEMBL1892413 | 0.85 | PPARG (0.60) | PPARGESR2 | |
| SCHEMBL4017163 | 0.83 | PPARG (0.62) | PPARGACHE | |
| SCHEMBL12737302 | 0.82 | PPARG (0.71) | PPARGACHE | |
| SCHEMBL4014913 | 0.82 | PPARG (0.49) | PPARGACHE | |
| SCHEMBL4016128 | 0.81 | PPARG (0.60) | PPARGACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |