Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010868 | 0.95 | PPARG (0.55) | PPARGACHEAGTR2 | |
| SCHEMBL1890245 | 0.89 | PPARG (0.50) | PPARGACHEAGTR1 | |
| SCHEMBL4016615 | 0.88 | PPARG (0.54) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL4009715 | 0.87 | PPARG (0.53) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL4013553 | 0.86 | PPARG (0.49) | PPARGACHE | |
| SCHEMBL4014315 | 0.85 | PPARG (0.44) | PPARGAGTR1AGTR2 | |
| SCHEMBL4012027 | 0.84 | PPARG (0.63) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL1889717 | 0.84 | PPARG (0.56) | PPARGACHEAGTR1 | |
| SCHEMBL4008828 | 0.83 | AGTR1 (0.42) | PPARGAGTR1AGTR2 | |
| SCHEMBL4017757 | 0.82 | PPARG (0.60) | PPARGACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |