Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11014464 | 1.00 | CHRM2 (0.37) | CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL7354701 | 1.00 | CHRM2 (0.37) | CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL10816801 | 1.00 | CHRM2 (0.37) | CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL11015957 | 1.00 | CHRM2 (0.37) | CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL10815644 | 1.00 | CHRM2 (0.37) | CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL10817753 | 0.98 | CHRM2 (0.35) | CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL10588318 | 0.98 | CHRM2 (0.35) | CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL2460430 | 0.98 | CHRM2 (0.35) | CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL5183989 | 0.98 | CHRM2 (0.35) | CHRM2CHRM4CHRM3CHRM1 | |
| SCHEMBL10818536 | 0.98 | CHRM2 (0.35) | CHRM2CHRM4CHRM3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854140-B1 | Vitronectin receptor antagonists, their production and their use | SANOFI AVENTIS DEUTSCHLAND (DE) | 2013-11-06 | — | — | EP | disclosed |
| EP-0903353-B1 | Imidazolidine derivates, their preparation and use, and pharmaceutical compositions containing them | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-11-25 | — | — | EP | disclosed |
| EP-0820988-B1 | Imino derivatives as bone resorption inhibitors and vitronectin receptor antagonists | HOECHST AG (DE) | 2009-07-01 | — | — | EP | disclosed |
| EP-0842944-B1 | Heterocycles as inhibitors of leukocyte adhesion and as antagonists of VLA-4 | HOECHST AG (DE) | 2003-07-09 | — | — | EP | disclosed |
| EP-0918059-B1 | Substituted imidazoline derivatives, their preparation, their use, and pharmaceutical compositions containing them | AVENTIS PHARMA GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| EP-0842945-B1 | Heterocycles as inhibitors of leukocyte adhesion and as antagonists of VLA-4 | HOECHST AG (DE) | 2003-02-19 | — | — | EP | disclosed |
| EP-0739898-B1 | Phosphonomonoester nucleic acids, methods for their preparation and their use | AVENTIS PHARMA GMBH (DE) | 2001-09-26 | — | — | EP | disclosed |
| EP-1077994-A1 | IMIDAZOLIDINE DERIVATIVES, THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME | Aventis Pharma Deutschland GmbH (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999060015-A1 | IMIDAZOLIDINE DERIVATIVES, THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-11-25 | — | — | WO | disclosed |
| EP-0918059-A1 | Substituted imidazoline derivatives, their preparation, their use, and pharmaceutical compositions containing them | Hoechst Marion Roussel Deutschland GmbH (DE) | 1999-05-26 | — | — | EP | disclosed |
| WO-1993018057-A1 | 4-OXO-2 THIOXOIMIDAZOLIDINE DERIVATES AS INHIBITORS OF BLOOD PLATELET AGGREGATION | CASSELLA AKTIENGESELLSCHAFT (DE) | 1993-09-16 | — | — | WO | disclosed |
| EP-0541946-A1 | Process for diastereo selective reductive pinacol-coupling of homochiral alpha-aminoaldehydes | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0496393-A1 | Alkylation of azaglycine derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-29 | — | — | EP | disclosed |
| EP-0475184-A1 | Process for the production of peptides by solid phase synthesis | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-18 | — | — | EP | disclosed |
| EP-0455133-A2 | Peptide antagonists of bradykinin | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-06 | — | — | EP | disclosed |
| EP-0449079-A2 | Hydantoin derivative | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-02 | — | — | EP | disclosed |
| EP-0435059-A1 | Retroviral protease inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-03 | — | — | EP | disclosed |
| EP-0428849-A2 | Retroviral protease inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-29 | — | — | EP | disclosed |
| EP-0413277-A1 | Peptide antagonists of bradykinin | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-20 | — | — | EP | disclosed |
| EP-0297620-A2 | Process for the preparation of byciclic aminocarboxylic acids, intermediates for this process and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-04 | — | — | EP | disclosed |