SCHEMBL7354701

SCHEMBL7354701

O=C(O)OC1CC2CCCCCCC2N1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 5/20 0.37
CHRM4 P08173 5/20 0.37
CHRM3 P20309 5/20 0.37
CHRM1 P11229 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11014464 1.00 CHRM2 (0.37) CHRM2CHRM4CHRM3CHRM1
SCHEMBL4018006 1.00 CHRM2 (0.37) CHRM2CHRM4CHRM3CHRM1
SCHEMBL10816801 1.00 CHRM2 (0.37) CHRM2CHRM4CHRM3CHRM1
SCHEMBL11015957 1.00 CHRM2 (0.37) CHRM2CHRM4CHRM3CHRM1
SCHEMBL10815644 1.00 CHRM2 (0.37) CHRM2CHRM4CHRM3CHRM1
SCHEMBL10817753 0.98 CHRM2 (0.35) CHRM2CHRM4CHRM3CHRM1
SCHEMBL10588318 0.98 CHRM2 (0.35) CHRM2CHRM4CHRM3CHRM1
SCHEMBL2460430 0.98 CHRM2 (0.35) CHRM2CHRM4CHRM3CHRM1
SCHEMBL5183989 0.98 CHRM2 (0.35) CHRM2CHRM4CHRM3CHRM1
SCHEMBL10818536 0.98 CHRM2 (0.35) CHRM2CHRM4CHRM3CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0739898-B1 Phosphonomonoester nucleic acids, methods for their preparation and their use AVENTIS PHARMA GMBH (DE) 2001-09-26 EP disclosed
EP-0503561-B1 Method for the diastereoselective reductive pinacol coupling of homochiral alpha aminoaldehydes HOECHST AG (DE) 1998-10-28 EP disclosed
EP-0435059-B1 Retroviral protease inhibitors HOECHST AG (DE) 1997-11-05 EP disclosed
EP-0739898-A2 Phosphonomonoester nucleic acids, methods for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1996-10-30 EP disclosed
EP-0541946-B1 Process for diastereo selective reductive pinacol-coupling of homochiral alpha-aminoaldehydes HOECHST AG (DE) 1996-07-17 EP disclosed
EP-0449079-B1 Hydantoin derivative CASSELLA FARBWERKE MAINKUR AG (DE) 1995-11-15 EP disclosed
EP-0649426-A1 INHIBITORS OF RETROVIRAL PROTEASES HOECHST AKTIENGESELLSCHAFT (DE) 1995-04-26 EP disclosed
EP-0496393-B1 Alkylation of azaglycine derivatives HOECHST AG (DE) 1995-01-25 EP disclosed
WO-1994000461-A1 INHIBITORS OF RETROVIRAL PROTEASES HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-06 WO disclosed
EP-0564972-A2 Peptides with N-terminal modifications having bradykinin antagonistic activity HOECHST AKTIENGESELLSCHAFT (DE) 1993-10-13 EP disclosed
EP-0541946-A1 Process for diastereo selective reductive pinacol-coupling of homochiral alpha-aminoaldehydes HOECHST AKTIENGESELLSCHAFT (DE) 1993-05-19 EP disclosed
EP-0503561-A2 Method for the diastereoselective reductive pinacol coupling of homochiral alpha aminoaldehydes HOECHST AKTIENGESELLSCHAFT (DE) 1992-09-16 EP disclosed
EP-0496393-A1 Alkylation of azaglycine derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-29 EP disclosed
EP-0455133-A2 Peptide antagonists of bradykinin HOECHST AKTIENGESELLSCHAFT (DE) 1991-11-06 EP disclosed
EP-0449079-A2 Hydantoin derivative HOECHST AKTIENGESELLSCHAFT (DE) 1991-10-02 EP disclosed
EP-0435059-A1 Retroviral protease inhibitors HOECHST AKTIENGESELLSCHAFT (DE) 1991-07-03 EP disclosed
EP-0428849-A2 Retroviral protease inhibitors HOECHST AKTIENGESELLSCHAFT (DE) 1991-05-29 EP disclosed
EP-0413277-A1 Peptide antagonists of bradykinin HOECHST AKTIENGESELLSCHAFT (DE) 1991-02-20 EP disclosed