⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20212144 | 0.79 | — | — | |
| SCHEMBL21998286 | 0.73 | — | — | |
| SCHEMBL1663749 | 0.69 | — | — | |
| SCHEMBL6995759 | 0.69 | — | — | |
| SCHEMBL148930 | 0.69 | MEN1 (0.47) | — | |
| SCHEMBL132519 | 0.69 | MEN1 (0.38) | — | |
| SCHEMBL17075902 | 0.69 | GRM4 (0.32) | — | |
| SCHEMBL2351528 | 0.67 | MEN1 (0.37) | — | |
| SCHEMBL25218451 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL9755283 | 0.67 | MEN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093013-A1 | FUSED THIOPHENE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA S.A. (BE) | 2009-07-30 | — | — | WO | disclosed |
| CN-1123573-C | 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors | BAYER AG (DE) | 2003-10-08 | — | — | CN | disclosed |
| WO-2001012707-A1 | METHODS FOR IMPROVING THE INSULATING PROPERTIES OF CLOSED CELLED RIGID POLYURETHANE FOAMS | HUNSTMAN INTERNATIONAL LLC (US) | 2001-02-22 | — | — | WO | disclosed |
| EP-0025846-B1 | IMPROVED PROCESS FOR THE PREPARATION OF VINYLCYCLOPROPANE DERIVATIVES | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1984-03-07 | — | — | EP | disclosed |
| EP-0010299-B1 | PHARMACEUTICAL COMPOSITION USEFUL FOR THE TREATMENT OF HYPERCHOLESTEREMIA | MERCK & CO. INC. (US) | 1984-02-15 | — | — | EP | disclosed |
| EP-0010299-A1 | Pharmaceutical composition useful for the treatment of hypercholesteremia | MERCK & CO. INC. (US) | 1980-04-30 | — | — | EP | disclosed |