⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5464728 | 0.72 | — | — | |
| SCHEMBL4018045 | 0.69 | — | — | |
| SCHEMBL178124 | 0.67 | — | — | |
| SCHEMBL1164835 | 0.67 | — | — | |
| Tromethamine SCHEMBL10455580 | 0.67 | MEN1 (0.83) | — | |
| Tromethamine SCHEMBL11155260 | 0.64 | MEN1 (0.77) | — | |
| Tromethamine SCHEMBL4950340 | 0.64 | MEN1 (0.77) | — | |
| Tromethamine SCHEMBL3696191 | 0.64 | — | — | |
| SCHEMBL1032719 | 0.64 | — | — | |
| SCHEMBL1985220 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698459-A | 1-phenyl-2-pyridylalkyl alcohol derivatives as phosphodiesterase inhibitors | 奇斯药制品公司 | 2020-01-17 | — | — | CN | disclosed |
| EP-2306994-B1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | AMGEN INC (US) | 2013-08-14 | — | — | EP | disclosed |
| EP-2306994-A1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | Amgen, Inc (US) | 2011-04-13 | — | — | EP | disclosed |
| US-7842685-B2 | S1P1 receptor agonists and use thereof | AMGEN INC. (US) | 2010-11-30 | — | — | US | disclosed |
| US-20100029611-A1 | S1P1 receptor agonists and use thereof | AMGEN INC. (US) | 2010-02-04 | — | — | US | disclosed |
| WO-2009154775-A1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | AMGEN INC. (US) | 2009-12-23 | — | — | WO | disclosed |
| US-4438260-A | Sisomicin compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1984-03-20 | — | — | US | disclosed |
| EP-0056575-A1 | Sisomicin derivatives, process for their preparation and their use as pharmaceutical compositions | BAYER AG (DE) | 1982-07-28 | — | — | EP | disclosed |