SCHEMBL4018049

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4015283	0.90	KDR (0.53)	KDRPNLIPMALT1LMNAKMT2A
	SCHEMBL1939656	0.90	KDR (0.52)	KDRPNLIPMALT1LMNAKMT2A
	SCHEMBL4023108	0.89	KDR (0.61)	KDRPNLIPLMNAKMT2APKM
	SCHEMBL4018876	0.89	KDR (0.61)	KDRLMNAKMT2APKML3MBTL1
	SCHEMBL4021290	0.88	KDR (0.70)	KDRLMNAKMT2APKML3MBTL1
	SCHEMBL1941283	0.87	KDR (0.50)	KDRPNLIPMALT1LMNAKMT2A
	SCHEMBL1940208	0.87	KDR (0.49)	KDRPNLIPMALT1LMNAKMT2A
	SCHEMBL4023799	0.85	KDR (0.78)	KDRLMNAKMT2APKML3MBTL1
	SCHEMBL13844055	0.85	KDR (0.47)	KDRPNLIPMALT1LMNAKMT2A
	SCHEMBL4017143	0.85	KDR (0.70)	KDRKMT2APKML3MBTL1FLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.