SCHEMBL4015283

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4018049	0.90	KDR (0.66)	KDRPNLIPMALT1LMNAPKM
	SCHEMBL13844055	0.89	KDR (0.47)	KDRPNLIPMALT1LMNAPKM
	SCHEMBL4021015	0.86	KDR (0.56)	KDRPKML3MBTL1MAPTSMN1; SMN2
	SCHEMBL1939656	0.85	KDR (0.52)	KDRPNLIPMALT1LMNAMAPT
	SCHEMBL1941283	0.83	KDR (0.50)	KDRPNLIPMALT1LMNAMAPT
	SCHEMBL1940208	0.83	KDR (0.49)	KDRPNLIPMALT1LMNAMAPT
	SCHEMBL4017151	0.81	KDR (0.78)	KDRLMNAPKML3MBTL1MAPT
	SCHEMBL1942131	0.81	KDR (0.47)	KDRPNLIPMALT1LMNAMAPT
	SCHEMBL15314445	0.80	KDR (0.54)	KDRLMNAPKML3MBTL1MAPT
	SCHEMBL1942411	0.80	KDR (0.47)	KDRPNLIPMALT1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.