SCHEMBL4018052

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4018762	0.89	KDR (0.64)	KDRFADS1L3MBTL1PKMALDH1A1
	SCHEMBL4021297	0.87	KDR (0.53)	KDRL3MBTL1PKMALDH1A1CYP2C9
	SCHEMBL1940427	0.84	FADS1 (0.52)	KDRFADS1L3MBTL1PKMALDH1A1
	SCHEMBL4028532	0.84	KDR (0.55)	KDRFADS1L3MBTL1PKMALDH1A1
	SCHEMBL4019641	0.83	KDR (0.56)	KDRL3MBTL1PKMALDH1A1CYP2C9
	Hydrochloric Acid SCHEMBL1941720	0.83	FADS1 (0.51)	KDRFADS1L3MBTL1PKMALDH1A1
	SCHEMBL4023718	0.83	KDR (0.55)	KDRL3MBTL1PKMALDH1A1CYP2C9
	SCHEMBL1941134	0.82	KDR (0.48)	KDRFADS1L3MBTL1PKMCYP2C9
	SCHEMBL1941539	0.81	KDR (0.47)	KDRFADS1L3MBTL1PKMALDH1A1
	SCHEMBL4016786	0.81	KDR (0.56)	KDRL3MBTL1PKMALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.