Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10606364 | 0.79 | KCNN4 (0.50) | MAPTNPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL2795435 | 0.73 | CYP2C9 (0.55) | MAPTNPC1RAB9AALOX15ALDH1A1 | |
| SCHEMBL2327512 | 0.73 | CA1 (0.52) | MAPTNPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL5144776 | 0.73 | CA1 (0.52) | MAPTNPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL4232572 | 0.73 | CA1 (0.52) | MAPTNPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL10813846 | 0.72 | CA1 (0.53) | MAPTNPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL1371089 | 0.72 | MAPT (0.51) | MAPTNPC1RAB9AALOX15ALDH1A1 | |
| SCHEMBL6404526 | 0.72 | MAPT (0.51) | MAPTNPC1RAB9AALOX15ALDH1A1 | |
| SCHEMBL1507665 | 0.71 | CA1 (0.54) | MAPTNPC1RAB9ASMN1; SMN2ALOX15 | |
| Bromomethane SCHEMBL3169542 | 0.70 | CYP2C9 (0.52) | MAPTRAB9AALOX15ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009092293-A1 | PYROLLIDINE-BASED COMPOUNDS | SHANGHAI TARGETDRUG CO., LTD. (CN) | 2009-07-30 | — | — | WO | disclosed |
| WO-2009089659-A1 | PYROLLIDINE-BASED COMPOUNDS | SHANGHAI TARGETDRUG CO., LTD. (CN) | 2009-07-23 | — | — | WO | disclosed |