SCHEMBL4018161

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4017524	0.85	KDR (0.65)	VCPKDRKMT2ANPC1ALDH1A1
	SCHEMBL4019283	0.84	KDR (0.64)	KDRMAOBKMT2AMEN1NPC1
	SCHEMBL4019414	0.83	KDR (0.71)	KDRKMT2ANPC1ALDH1A1RAB9A
	SCHEMBL4017789	0.82	KDR (0.70)	KDRKMT2AMEN1NPC1ALDH1A1
	SCHEMBL4020715	0.82	KDR (0.64)	KDRKMT2AMEN1NPC1RAB9A
	SCHEMBL4016715	0.82	KDR (0.79)	KDRKMT2AMEN1NPC1ALDH1A1
	SCHEMBL4023085	0.81	KDR (0.69)	KDRKMT2ANPC1ALDH1A1RAB9A
	SCHEMBL4019331	0.81	KDR (0.68)	KDRKMT2AMEN1ALDH1A1TP53
	SCHEMBL4018167	0.81	KDR (0.65)	KDRKMT2AALDH1A1TP53SMN1; SMN2
	SCHEMBL4015002	0.81	KDR (0.71)	KDRKMT2AMEN1NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.