Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.66 |
| ▸ | CTSK | P43235 | 6/20 | 0.66 |
| ▸ | CTSB | P07858 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | CCKBR | P32239 | 3/20 | 0.51 |
| ▸ | CCKAR | P32238 | 3/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018237 | 1.00 | CTSS (0.66) | CTSSCTSKCTSBCTSLOPRD1 | |
| SCHEMBL11683746 | 1.00 | CTSS (0.66) | CTSSCTSKCTSBCTSLOPRD1 | |
| SCHEMBL31181953 | 0.92 | CTSS (0.77) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL11345783 | 0.91 | CTSS (0.63) | CTSSCTSKCTSBCTSLOPRD1 | |
| SCHEMBL19944788 | 0.89 | CTSS (0.64) | CTSSCTSKCTSBCTSLOPRD1 | |
| SCHEMBL11122782 | 0.89 | CTSS (0.69) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL11365513 | 0.88 | CTSS (0.68) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL9819589 | 0.88 | CTSS (0.59) | CTSSCTSKCTSBCTSLOPRD1 | |
| SCHEMBL11124222 | 0.88 | CTSS (0.71) | CTSSCTSKCTSBCTSLPTPN1 | |
| SCHEMBL29670127 | 0.88 | CTSS (0.51) | CTSSCTSKCTSBCTSLPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093918-A1 | A METHOD OF PRODUCING AN N-BLOCKED BIPHALIN INTERMEDIATE | INSTYTUT MEDYCYNY DOSWIADCZALNEJ I KLINICZNEJ IM. (PL) | 2009-07-30 | — | — | WO | disclosed |
| US-4593098-A | Piperazinone and piperazine polypeptides | THE UPJOHN COMPANY (US) | 1986-06-03 | — | — | US | disclosed |
| US-4534897-A | Piperazinone, piperazine, 1,4-diazepin-2-one and 1,4-diazepine intermediate compounds | THE UPJOHN COMPANY (US) | 1985-08-13 | — | — | US | disclosed |
| EP-0033504-B1 | PENTAPEPTIDES OF THE ENCEPHALINE TYPE, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1984-10-24 | — | — | EP | disclosed |
| EP-0030846-B1 | PHARMACOLOGICALLY ACTIVE PEPTIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ELI LILLY AND COMPANY (US) | 1984-05-09 | — | — | EP | disclosed |
| US-4339440-A | HYPOTENSIVES | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1982-07-13 | — | — | US | disclosed |
| EP-0001684-B1 | TETRAPEPTIDES, METHODS FOR THEIR PREPARATION AND THEIR USE IN ANALGESIC COMPOSITIONS | ELI LILLY AND COMPANY (US) | 1981-09-02 | — | — | EP | disclosed |
| EP-0033504-A2 | Pentapeptides of the encephaline type, process for their preparation and medicaments containing these | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1981-08-12 | — | — | EP | disclosed |
| EP-0030846-A2 | Pharmacologically active peptides, their preparation and pharmaceutical compositions containing them | ELI LILLY AND COMPANY (US) | 1981-06-24 | — | — | EP | disclosed |
| US-4273704-A | N-Adamantane-substituted tetrapeptide amides | G. D. SEARLE & CO. (US) | 1981-06-16 | — | — | US | disclosed |
| US-4251438-A | ANALGESICS, PSYCHOTHERAPEUTIC AGENTS | THE UPJOHN COMPANY (US) | 1981-02-17 | — | — | US | disclosed |
| EP-0001684-A2 | Tetrapeptides, methods for their preparation and their use in analgesic compositions | ELI LILLY AND COMPANY (US) | 1979-05-02 | — | — | EP | disclosed |