Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Morpholine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL14957611 | 1.00 | MEN1 (0.65) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL11524539 | 1.00 | MEN1 (0.65) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL9998476 | 0.97 | MEN1 (0.61) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL9998486 | 0.97 | MEN1 (0.61) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL3822897 | 0.91 | MEN1 (0.61) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL3822890 | 0.91 | MEN1 (0.61) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL28322795 | 0.90 | — | — | |
| Morpholine SCHEMBL5707215 | 0.88 | MEN1 (0.58) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL29207396 | 0.88 | KMT2A (0.58) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL9998470 | 0.88 | KDM4E (0.58) | MEN1KMT2AKDM4EGAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115486446-A | Efficient cyhalothrin and preparation method thereof | 武汉地美达环境科技有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-113195699-A | Detergent composition and washing method using same | 凯斯科技股份有限公司 | 2021-07-30 | — | — | CN | claimed |
| EP-1846422-B1 | ORGANIC SILVER COMPLEXES, THEIR PREPARATION METHODS AND THEIR METHODS FOR FORMING THIN LAYERS | INKTEC CO LTD (KR) | 2016-04-13 | — | — | EP | claimed |
| US-7494630-B2 | Method of stripping metals from organic solvents | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 2009-02-24 | — | — | US | claimed |
| US-20070189943-A1 | Method of stripping metals from organic solvents | ENERGY, UNITED STATES DEPARTMENT OF | 2007-08-16 | — | — | US | claimed |
| CN-116444392-B | Polypeptide protein medicine oral absorption promoter and preparation method and application thereof | 中国药科大学 | 2024-09-27 | — | — | CN | disclosed |
| US-20240030448-A1 | CONDUCTIVE MATERIAL DISPERSION, AND METHODS FOR MANUFACTURING POSITIVE ELECTRODE FOR LITHIUM ION SECONDARY BATTERY AND LITHIUM ION SECONDARY BATTERY USING SAME | MIKUNI SHIKISO KABUSHIKI KAISHA (JP) | 2024-01-25 | — | — | US | disclosed |
| CN-113195699-B | Detergent composition and washing method using the same | 凯斯科技股份有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-116444392-A | Polypeptide protein medicine oral absorption promoter and preparation method and application thereof | 中国药科大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-115486446-A | Efficient cyhalothrin and preparation method thereof | 武汉地美达环境科技有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-114982004-A | Conductive material dispersion liquid for positive electrode of lithium ion secondary battery and electrode slurry | 御国色素株式会社 | 2022-08-30 | — | — | CN | disclosed |
| CN-113195699-A | Detergent composition and washing method using same | 凯斯科技股份有限公司 | 2021-07-30 | — | — | CN | disclosed |
| WO-2006083153-A1 | ORGANIC SILVER COMPLEXES, THEIR PREPARATION METHODS AND THEIR METHODS FOR FORMING THIN LAYERS | INKTEC CO., LTD. (KR) | 2006-08-10 | — | — | WO | disclosed |
| EP-0426087-B1 | Dye fixing material | FUJI PHOTO FILM CO LTD (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5089378-A | Method for forming an image | FUJI PHOTO FILM CO., LTD. (JP) | 1992-02-18 | — | — | US | disclosed |
| EP-0426087-A2 | Dye fixing material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |
| US-4729942-A | PREVENTING EARLY COLOR DIFFUSION BY USING A DYE DEVELOPER HAVING A DYE MOITY HAVING A HYDROLYZABLE ESTER BALLAST GROUP; PHOTOTHERMOGRAPHY; SILVER HALIDES; | FUJI PHOTO FILM CO., LTD. (JP) | 1988-03-08 | — | — | US | disclosed |
| US-4704345-A | COLOR PHOTOGRAPHY, DIFFUSION TRANSFER, THERMOGRAPHY | FUJI PHOTO FILM CO., LTD. (JP) | 1987-11-03 | — | — | US | disclosed |
| US-4145303-A | LEWIS BASE, ZINC OR ZIRCONIUM COORDINATION COMPOUND, AND A FLUOROALIPHATIC ACID | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1979-03-20 | — | — | US | disclosed |
| US-4101328-A | ZINC-SURFACED STEEL SUBSTRATE, PH ADJUSTING AMINE | A. F. INDUSTRIES, INC. (US) | 1978-07-18 | — | — | US | disclosed |