Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Morpholine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL9998476 | 1.00 | MEN1 (0.61) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL4018377 | 0.97 | MEN1 (0.65) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL11524539 | 0.97 | MEN1 (0.65) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL14957611 | 0.97 | MEN1 (0.65) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL3822897 | 0.88 | MEN1 (0.61) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL3822890 | 0.88 | MEN1 (0.61) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL28322795 | 0.87 | — | — | |
| Morpholine SCHEMBL5707215 | 0.86 | MEN1 (0.58) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL29207396 | 0.86 | KMT2A (0.58) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL9998470 | 0.86 | KDM4E (0.58) | MEN1KMT2AKDM4EGAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3444089-B1 | PREPREG, FIBER-REINFORCED COMPOSITE MATERIAL AND SURFACE-MODIFIED REINFORCING FIBERS | TEIJIN LTD (JP) | 2024-02-28 | — | — | EP | disclosed |
| US-11352472-B2 | Prepreg, fiber-reinforced composite material and surface-modified reinforcing fibers | TEIJIN LIMITED (JP) | 2022-06-07 | — | — | US | disclosed |
| EP-3444089-A1 | PREPREG, FIBER-REINFORCED COMPOSITE MATERIAL AND SURFACE-MODIFIED REINFORCING FIBERS | Teijin Limited (JP) | 2019-02-20 | — | — | EP | disclosed |
| US-9759844-B2 | Film mirror, film mirror manufacturing method, film mirror for photovoltaic power generation, and reflection device for photovoltaic power generation | Konica Minolta, Inc. (JP) | 2017-09-12 | — | — | US | disclosed |
| US-9299483-B2 | Method for manufacturing transparent conductive film | INKTEC CO., LTD. (KR) | 2016-03-29 | — | — | US | disclosed |
| US-9290844-B2 | Method for preparing metallic thin film | INKTEC CO., LTD. (KR) | 2016-03-22 | — | — | US | disclosed |
| US-20150116820-A1 | FILM MIRROR FOR SOLAR LIGHT REFLECTION, AND REFLECTIVE DEVICE FOR SOLAR POWER GENERATION | Konica Minolta, Inc. (JP) | 2015-04-30 | — | — | US | disclosed |
| US-20140340741-A1 | FILM MIRROR, FILM MIRROR MANUFACTURING METHOD, FILM MIRROR FOR PHOTOVOLTAIC POWER GENERATION, AND REFLECTION DEVICE FOR PHOTOVOLTAIC POWER GENERATOR | Konica Minolta, Inc. (JP) | 2014-11-20 | — | — | US | disclosed |
| EP-2801847-A1 | FILM MIRROR, FILM MIRROR MANUFACTURING METHOD, FILM MIRROR FOR PHOTOVOLTAIC POWER GENERATION, AND REFLECTION DEVICE FOR PHOTOVOLTAIC POWER GENERATION | Konica Minolta, Inc. (JP) | 2014-11-12 | — | — | EP | disclosed |
| EP-2796904-A1 | FILM MIRROR FOR SOLAR LIGHT REFLECTION, AND REFLECTIVE DEVICE FOR SOLAR POWER GENERATION | Konica Minolta, Inc. (JP) | 2014-10-29 | — | — | EP | disclosed |
| US-20130118786-A1 | Method for Manufacturing Transparent Conductive Film and Transparent Conductive Film Manufactured Thereby | INKTEC CO., LTD. (KR) | 2013-05-16 | — | — | US | disclosed |
| US-20110318481-A1 | Method for Preparing Metallic Thin Film | INKTEC CO., LTD. (KR) | 2011-12-29 | — | — | US | disclosed |