SCHEMBL4018400

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4021577	0.89	KDR (0.73)	KDRHSD17B10POLBALOX15ALDH1A1
	SCHEMBL4015093	0.85	KDR (0.78)	KDRHSD17B10POLBALOX15ALDH1A1
	SCHEMBL4017944	0.85	KDR (0.72)	KDRALOX15ALDH1A1LMNATP53
	SCHEMBL4023802	0.84	KDR (0.69)	KDRHSD17B10POLBALOX15NAMPT
	SCHEMBL4019386	0.83	KDR (1.00)	KDRHSD17B10POLBALOX15MAPK1
	SCHEMBL4186980	0.82	KDR (0.73)	KDRHSD17B10POLBALOX15ALDH1A1
	SCHEMBL4017225	0.82	KDR (0.73)	KDRHSD17B10POLBALOX15ALDH1A1
	SCHEMBL4015708	0.82	KDR (0.73)	KDRHSD17B10POLBALOX15NAMPT
	SCHEMBL4021315	0.81	KDR (0.75)	KDRHSD17B10POLBALOX15NAMPT
	SCHEMBL4015775	0.81	ALDH1A1 (0.54)	KDRHSD17B10ALDH1A1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.