SCHEMBL4018587

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4015976	0.91	KDR (0.64)	LMNAKDRTDP1SMN1; SMN2ALDH1A1
	SCHEMBL4021290	0.91	KDR (0.70)	LMNAKDRTDP1SMN1; SMN2ALDH1A1
	SCHEMBL4023756	0.90	KDR (0.64)	LMNAKDRTDP1SMN1; SMN2ALDH1A1
	SCHEMBL4024905	0.89	KDR (0.61)	LMNAKDRTDP1SMN1; SMN2ALDH1A1
	SCHEMBL4017009	0.86	KDR (0.74)	LMNAKDRSMN1; SMN2ALDH1A1RAB9A
	SCHEMBL4021262	0.86	KDR (0.64)	LMNAKDRSMN1; SMN2ALDH1A1HTT
	SCHEMBL4017456	0.85	KDR (0.67)	LMNAKDRSMN1; SMN2ALDH1A1KDM4E
	SCHEMBL4015236	0.85	KDR (0.66)	LMNAKDRTDP1SMN1; SMN2ALDH1A1
	SCHEMBL4019414	0.84	KDR (0.71)	LMNAKDRSMN1; SMN2ALDH1A1HTT
	SCHEMBL4023378	0.83	KDR (0.84)	KDRSMN1; SMN2ALDH1A1HTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.