Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | LPO | P22079 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbon Monoxide SCHEMBL4025173 | 0.65 | MAPK1 (0.38) | KDM4ECA1MAPK1LPOPTGS1 | |
| SCHEMBL19323693 | 0.61 | — | — | |
| SCHEMBL33270 | 0.59 | — | — | |
| SCHEMBL20412726 | 0.59 | GAA (0.38) | KDM4ECA1MAPK1LPOPTGS1 | |
| SCHEMBL4478455 | 0.59 | HPGD (0.46) | KDM4ECA1MAPK1LPOPTGS1 | |
| SCHEMBL4848024 | 0.58 | NOTUM (0.37) | KDM4ECA1MAPK1LPOPTGS1 | |
| SCHEMBL21341793 | 0.57 | KDM4E (0.43) | KDM4ECA1MAPK1LPOPTGS1 | |
| SCHEMBL28170050 | 0.56 | KDM4E (0.38) | KDM4ECA1MAPK1LPOPTGS1 | |
| SCHEMBL12360767 | 0.56 | — | — | |
| SCHEMBL1926137 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209777-A1 | ORGANOMETALLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND METHODS OF USE THEREOF | PRAXAIR TECHNOLOGY, INC. | 2009-08-20 | — | — | US | claimed |
| WO-2009094262-A1 | ORGANOMETALLIC COMPOUNDS, PROCESSES AND METHODS OF USE | PRAXAIR TECHNOLOGY, INC. (US) | 2009-07-30 | — | — | WO | claimed |
| US-20090205968-A1 | ORGANOMETALLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND METHODS OF USE THEREOF | PRAXAIR TECHNOLOGY, INC. | 2009-08-20 | — | — | US | disclosed |
| US-20090209777-A1 | ORGANOMETALLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND METHODS OF USE THEREOF | PRAXAIR TECHNOLOGY, INC. | 2009-08-20 | — | — | US | disclosed |
| US-20090205538-A1 | ORGANOMETALLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND METHODS OF USE THEREOF | PRAXAIR TECHNOLOGY, INC. | 2009-08-20 | — | — | US | disclosed |
| WO-2009094262-A1 | ORGANOMETALLIC COMPOUNDS, PROCESSES AND METHODS OF USE | PRAXAIR TECHNOLOGY, INC. (US) | 2009-07-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090205538-A1 | ORGANOMETALLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND METHODS OF USE THEREOF | L1CAM, AP2M1, AP1M1 | KDM4E 416/4885CA1 2482/4885MAPK1 2730/4885 |
| US-20090209777-A1 | ORGANOMETALLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND METHODS OF USE THEREOF | L1CAM, AP2M1, AP1M1 | KDM4E 416/4885CA1 2482/4885MAPK1 2730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.