Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | IDE | P14735 | 2/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583500 | 0.89 | ALDH1A1 (0.57) | MAPK1NPSR1ALDH1A1MAPTPKM | |
| SCHEMBL14183875 | 0.86 | ALDH1A1 (0.56) | MAPK1NPSR1ALDH1A1MAPTPKM | |
| SCHEMBL14183873 | 0.80 | ALDH1A1 (0.54) | MAPK1ALDH1A1MAPTPKMMEN1 | |
| SCHEMBL4581343 | 0.79 | ALDH1A1 (0.58) | MAPK1NPSR1ALDH1A1MAPTPKM | |
| SCHEMBL4024461 | 0.79 | ALDH1A1 (0.60) | MAPK1ALDH1A1MAPTPKMMEN1 | |
| SCHEMBL4016317 | 0.79 | MAPK1 (0.59) | MAPK1NPSR1ALDH1A1MAPTPKM | |
| SCHEMBL4018148 | 0.78 | MAPK1 (0.60) | MAPK1NPSR1ALDH1A1MAPTPKM | |
| SCHEMBL4581795 | 0.77 | MAPK1 (0.58) | MAPK1NPSR1ALDH1A1MAPTPKM | |
| SCHEMBL4016311 | 0.77 | ALDH1A1 (0.57) | MAPK1NPSR1ALDH1A1MAPTPKM | |
| SCHEMBL4016159 | 0.77 | MAPK1 (0.57) | MAPK1NPSR1ALDH1A1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066654-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | Bayer Schering Pharma AG (DE) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008028691-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | disclosed |